Break Free from Treatment-Resistant Depression with Spravato® (esketamine)

Licensed in Tennessee and Virginia, serving patients in Kingsport, Bristol, and surrounding communities.

If you’ve tried antidepressants or therapy but still feel stuck, there’s a new option for relief. Spravato® (Esketamine) is an FDA-approved treatment for adults living with treatment-resistant depression (TRD).

At Open Minds, we provide Spravato® in a calm, supportive environment, guided by licensed professionals serving Tennessee and Virginia. You’ll receive personalized care every step of the way — safely, compassionately, and with hope.

Learn how Spravato® can help you today

How Spravato® (Esketamine) Works

Spravato® (Esketamine) contains esketamine, a medication that works differently from standard antidepressants. Instead of focusing on serotonin or dopamine, it acts on glutamate receptors in the brain — helping rebuild connections that affect mood, energy, and motivation.

Unlike most antidepressants that take weeks to work, many patients feel improvement within days. Spravato® (Esketamine) is administered as a nasal spray, under the care of your provider, in a quiet and peaceful treatment room.

Talk to our care team about Spravato®
Spravato nasal spray on table
Spravato esketamine nasal spray 84 mg dose kit with applicator displayed on a wooden surface

Who Can Benefit from Spravato® (esketamine)

Spravato® (Esketamine) may help if you:

  • Have treatment-resistant depression (TRD)
  • Have tried multiple antidepressants with limited results
  • Continue to feel hopeless, numb, or unmotivated
  • Want a safe, guided option beyond traditional medication

Your provider will discuss whether Spravato® (Esketamine) fits your needs and if it can be combined with your current therapy or prescriptions.

See if Spravato® (esketamine) is right for you

What to Expect During a Spravato® (esketamine) Session

Each session lasts about two hours and takes place in a relaxing environment:

Before Treatment

We review your health and medications.

During Treatment

You self-administer Spravato® (Esketamine) while your provider stays nearby.

Observation

Our care team monitors your comfort and safety for about 2 hours.

Aftercare

You’ll need a ride home and can return to normal activities the next day.

Why Choose Open Minds

  • Safe, evidence-based approach to treatment-resistent depression
  • Experienced team that includes psychiatrists, therapists, and nurses
  • Insurance support—we assist with pre-authorization for Spravato® (Esketamine)
  • Licensed in Tennessee & Virginia
Spravato nasal spray kit on table

Serving Kingsport, Bristol, and Nearby Communities

We proudly support families and adults across Kingsport, Bristol, Tennessee, Virginia, and nearby communities. In-person and telehealth appointments are available, making screening accessible no matter your location.

Find Your Nearest Location

Testimonials

Frequently Asked Questions

Still have questions? We're here to help.
Colorful logo with cozy seating area

Open Your Mind to a Better You

You don’t have to live with depression that won’t lift. With compassionate care and modern treatment, healing is possible. Let’s take this next step — together.

Schedule your Spravato® (Esketamine) consultation today