Break Free from Treatment-Resistant Depression with Spravato® (esketamine)
Licensed in Tennessee and Virginia, serving patients in Kingsport, Bristol, and surrounding communities.
If you’ve tried antidepressants or therapy but still feel stuck, there’s a new option for relief. Spravato® (Esketamine) is an FDA-approved treatment for adults living with treatment-resistant depression (TRD).
At Open Minds, we provide Spravato® in a calm, supportive environment, guided by licensed professionals serving Tennessee and Virginia. You’ll receive personalized care every step of the way — safely, compassionately, and with hope.


How Spravato® (Esketamine) Works
Spravato® (Esketamine) contains esketamine, a medication that works differently from standard antidepressants. Instead of focusing on serotonin or dopamine, it acts on glutamate receptors in the brain — helping rebuild connections that affect mood, energy, and motivation.
Unlike most antidepressants that take weeks to work, many patients feel improvement within days. Spravato® (Esketamine) is administered as a nasal spray, under the care of your provider, in a quiet and peaceful treatment room.


Who Can Benefit from Spravato® (esketamine)
Spravato® (Esketamine) may help if you:
- Have treatment-resistant depression (TRD)
- Have tried multiple antidepressants with limited results
- Continue to feel hopeless, numb, or unmotivated
- Want a safe, guided option beyond traditional medication
Your provider will discuss whether Spravato® (Esketamine) fits your needs and if it can be combined with your current therapy or prescriptions.
What to Expect During a Spravato® (esketamine) Session
Each session lasts about two hours and takes place in a relaxing environment:
Before Treatment
We review your health and medications.
During Treatment
You self-administer Spravato® (Esketamine) while your provider stays nearby.
Observation
Our care team monitors your comfort and safety for about 2 hours.
Aftercare
You’ll need a ride home and can return to normal activities the next day.
Why Choose Open Minds
- Safe, evidence-based approach to treatment-resistent depression
- Experienced team that includes psychiatrists, therapists, and nurses
- Insurance support—we assist with pre-authorization for Spravato® (Esketamine)
- Licensed in Tennessee & Virginia

Serving Kingsport, Bristol, and Nearby Communities
Testimonials
Frequently Asked Questions
What is Spravato® (Esketamine) treatment for depression?
Spravato® (Esketamine) is an FDA-approved nasal spray for adults with treatment-resistant depression. It’s administered under supervision by licensed providers at Open Minds.
Is Spravato® (Esketamine) safe and FDA-approved for treating depression in Tennessee and Virginia?
Yes. Spravato® (Esketamine) is FDA-approved and safely administered by licensed professionals in both states. Learn more from the U.S. Food and Drug Administration.
How soon can I feel results from Spravato® (Esketamine) depression treatment?
Many patients report noticeable improvements within the first 4–6 weeks. Your provider will monitor your progress carefully during treatment.
Does insurance cover Spravato® (Esketamine) treatment for depression in Kingsport, TN?
Most major insurance plans cover Spravato® (Esketamine) for treatment-resistant depression. Visit finance insurance for more information or check with our staff.
Can I receive both Spravato and therapy at Open Minds?
Yes. Spravato® (Esketamine) works best when combined with therapy or psychiatry. We coordinate your care to ensure full emotional support.
How is Spravato® (Esketamine) different from TMS therapy for depression?
Spravato® (Esketamine) uses Esketamine through nasal administration, while NeuroStar TMS uses magnetic stimulation. Your provider will help decide which fits your needs best.

Open Your Mind to a Better You
You don’t have to live with depression that won’t lift. With compassionate care and modern treatment, healing is possible. Let’s take this next step — together.
